BDBM162565 US9687479, 45 1-benzyl-3-(5-[(5-chlorothiophen-2-yl)methyl]amino-1-[(2,3-dihydro-1,4-benzodioxin-5-yl)carbonyl]-1H-pyrazol-3-yl)-1,2-dihydropyridin-2-one

SMILES Clc1ccc(CNc2cc(nn2C(=O)c2cccc3OCCOc23)-c2cccn(Cc3ccccc3)c2=O)s1

InChI Key InChIKey=LKMJVZQDGGVYNB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 162565   

TargetProthrombin(Human)
Verseon

US Patent
LigandPNGBDBM162565(US9687479, 45 1-benzyl-3-(5-[(5-chlorothiophen-2-y...)
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:Human thrombin was obtained from Haematologic Technologies Inc. The chromogenic substrate S-2238 was obtained from DiaPharma. Thrombin was assayed in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
Go to US Patent