BDBM162366 BDBM162611::US9687479, 3 3-(5-[(5-chlorothiophen-2-yl)methyl]amino-1-(2,2-dimethylpropanoyl)-1H-pyrazol-3-yl)-1,2-dihydropyridin-2-one
SMILES CC(C)(C)C(=O)n1nc(cc1NCc1ccc(Cl)s1)-c1ccc[nH]c1=O
InChI Key InChIKey=IELDEMOVCFANHT-UHFFFAOYSA-N
Data 14 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 162366
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:Human thrombin was obtained from Haematologic Technologies Inc. The chromogenic substrate S-2238 was obtained from DiaPharma. Thrombin was assayed in...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:Human thrombin was obtained from Haematologic Technologies Inc. The chromogenic substrate S-2238 was obtained from DiaPharma. Thrombin was assayed in...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human thrombin using S-2238 as chromogenic substrate preincubated for 10 mins followed by substrate addition and measured after 10 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human factor Xa using S-2765 as chromogenic substrate preincubated for 10 mins followed by substrate addition and measured after 10 min...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of factor VIIa (unknown origin) using S-2238 as chromogenic substrate preincubated for 10 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of factor IXa (unknown origin) using spectrozyme as substrate preincubated for 10 mins followed by substrate addition and measured after 1...More data for this Ligand-Target Pair
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of factor XIa (unknown origin) using S-2366 as chromogenic substrate preincubated for 10 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of factor XIIa (unknown origin) using S-2302 as chromogenic substrate preincubated for 10 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of activated protein C (unknown origin) using S-2366 as chromogenic substrate preincubated for 10 mins followed by substrate addition and ...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of chymotrypsin (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of plasmin (unknown origin) using S-2251 as chromogenic substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of trypsin (unknown origin) using S-2765 as chromogenic substrate preincubated for 10 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tryptase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of plasma kallikrein (unknown origin)More data for this Ligand-Target Pair