BDBM161637 US9108983, Example 456

SMILES C[C@@H]1Cc2ccccc2CN1C(=O)c1ccc(Cl)cc1-c1cc(C(=O)N(c2ccc(O)cc2)c2cnc(OCCN3CCOCC3)nc2)c(C)n1C

InChI Key InChIKey=DEGOFNAAIJRJOC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161637   

TargetApoptosis regulator Bcl-2(Human)
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US Patent
LigandPNGBDBM161637(US9108983, Example 456)
Affinity DataIC50: 2.70nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
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US Patent