BDBM161572 US9108983, Example 387::US9108984, 1

SMILES CC(Nc1ncnc(N)c1C#N)c1cc(Cl)c2ccnnc2c1-c1cccc(F)c1

InChI Key InChIKey=QWFVYNRPRHSZRP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 161572   

TargetApoptosis regulator Bcl-2(Human)
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US Patent
LigandPNGBDBM161572(US9108984, 1 | US9108983, Example 387)
Affinity DataIC50: 20.6nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
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LigandPNGBDBM161572(US9108984, 1 | US9108983, Example 387)
Affinity DataIC50: 20nMpH: 6.7 T: 2°CAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 uL. Inhibitors wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
Go to US Patent