BDBM161403 US10835536, Ex. Comp 16::US10894048, Ex Comp 16::US9108973, 16

SMILES COc1cc(OC)cc(c1)C#Cc1nn(C2CN(C2)C(=O)\C=C\CNC2CCC2)c2ncnc(N)c12

InChI Key InChIKey=NNQYORSUZKXWBM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 161403   

TargetFibroblast growth factor receptor 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161403(US9108973, 16 | US10894048, Ex Comp 16 | US1083553...)
Affinity DataIC50: 3.80nMpH: 7.5 T: 2°CAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161403(US9108973, 16 | US10894048, Ex Comp 16 | US1083553...)
Affinity DataIC50: 3.80nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM161403(US9108973, 16 | US10894048, Ex Comp 16 | US1083553...)
Affinity DataIC50: 3.80nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
Go to US Patent