BDBM16094 2-[(4-phenylbenzene)amido]benzoic acid::2-[(biphenyl-4-ylcarbonyl)amino]benzoic acid::Inhibitor 2

SMILES OC(=O)c1ccccc1NC(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=WXLRBDMDGLLZRS-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 16094   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))TBA
LigandPNGBDBM16094(2-[(biphenyl-4-ylcarbonyl)amino]benzoic acid | 2-[...)
Affinity DataIC50: 1.55E+5nMAssay Description:Inhibition of Plasmodium falciparum HIs6-tagged DHODH expressed in Escherichia coli DH5alpha using L-dihydroorotate as substrate by DCIP-based spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

LigandPNGBDBM16094(2-[(biphenyl-4-ylcarbonyl)amino]benzoic acid | 2-[...)
Affinity DataKi:  700nM ΔG°:  -8.39kcal/mole IC50: 5.00E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))TBA
LigandPNGBDBM16094(2-[(biphenyl-4-ylcarbonyl)amino]benzoic acid | 2-[...)
Affinity DataKi:  1.77E+4nM ΔG°:  -6.48kcal/mole IC50: 1.54E+5nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2007
Entry Details Article
PubMed