BDBM160814 US9682980, 8-Chloro-7-(4-(2,4-difluorophenyl)piperidin-1-yl)-3-(2,2,2-trifluoroethyl)-[1,2,4]triazolo[4,3-b]pyridazine

SMILES Fc1ccc(C2CCN(CC2)c2cnn3c(CC(F)(F)F)nnc3c2Cl)c(F)c1

InChI Key InChIKey=OEPRXBWVOXLRJV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160814   

TargetMetabotropic glutamate receptor 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160814(US9682980, 8-Chloro-7-(4-(2,4-difluorophenyl)piper...)
Affinity DataEC50:  16nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
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US Patent