BDBM160791 US9682980, 1′-(8-Chloro-3-(2,2,2-trifluoroethyl)-[1,2,4]triazolo[4,3-b]pyridazin-7-yl)-2H-spiro[benzofuran-3,4′-piperidin]-2-one

SMILES FC(F)(F)Cc1nnc2c(Cl)c(cnn12)N1CCC2(CC1)C1C=CC=CC1OC2=O

InChI Key InChIKey=RRNUXNSYUPJWRK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160791   

TargetMetabotropic glutamate receptor 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160791(US9682980, 1′-(8-Chloro-3-(2,2,2-trifluoroet...)
Affinity DataEC50:  185nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
In DepthDetails
US Patent