BDBM16078 (2R,4S,5S)-N-butyl-5-[(2S)-2-[(2S)-2-acetamido-N,4-dimethylpentanamido]propanamido]-4-hydroxy-2,7-dimethyloctanamide::open-chain analog 104

SMILES CCCCNC(=O)[C@H](C)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](C)N(C)C(=O)[C@H](CC(C)C)NC(C)=O

InChI Key InChIKey=NFAPUBHYOPMZSK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16078   

TargetBeta-secretase 1 [1-453](Human)
Universite De Montreal At Succursale Centre-Ville

LigandPNGBDBM16078((2R,4S,5S)-N-butyl-5-[(2S)-2-[(2S)-2-acetamido-N,4...)
Affinity DataIC50: 100nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetCathepsin D(Human)
Universite De Montreal At Succursale Centre-Ville

LigandPNGBDBM16078((2R,4S,5S)-N-butyl-5-[(2S)-2-[(2S)-2-acetamido-N,4...)
Affinity DataIC50: 190nMT: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed