BDBM160779 US9682980, 3-Benzyl-8-chloro-7-(4-phenylpiperidin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazine

SMILES Clc1c(cnn2c(Cc3ccccc3)nnc12)N1CCC(CC1)c1ccccc1

InChI Key InChIKey=RKAREHBKZROCDO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160779   

TargetMetabotropic glutamate receptor 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160779(US9682980, 3-Benzyl-8-chloro-7-(4-phenylpiperidin-...)
Affinity DataEC50:  217nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
In DepthDetails
US Patent