BDBM160510 US10280160, Example 2.::US9682969, 2

SMILES CN(C(=O)Cn1nc(-c2cccc(F)c2)c2ccccc2c1=O)c1ccc2nc(C)oc2c1

InChI Key InChIKey=TWWAQYCDMSRCBJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 160510   

LigandPNGBDBM160510(US9682969, 2 | US10280160, Example 2.)
Affinity DataEC50:  1.50E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCystic fibrosis transmembrane conductance regulator(Human)
Flatley Discovery Lab

US Patent
LigandPNGBDBM160510(US9682969, 2 | US10280160, Example 2.)
Affinity DataEC50: <1.00E+4nMAssay Description:Fisher Rat Thyroid (FRT) cells stably expressing both human F508del CFTR and a halide-sensitive yellow fluorescent protein (YFP-H148Q/I152L 25,22) (G...More data for this Ligand-Target Pair
In DepthDetails
US Patent