BDBM160088 US10047092, 29::US10053463, 29::US9040534, 29
SMILES C[C@H]1Cn2c(nnc2-c2cccnc2)C(=O)N1Cc1cccc(c1Cl)C(F)(F)F
InChI Key InChIKey=KRUNLDBOHJWLOR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 160088
Affinity DataIC50: 1nMpH: 7.4Assay Description:Ca2+ Flux: 1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium...More data for this Ligand-Target Pair
Affinity DataIC50: 122nMpH: 7.4Assay Description:Ca2+ Flux: 1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
Affinity DataIC50: 122nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Antagonist activity at rat P2X7 receptor expressed in 1321N1 cells assessed as inhibition of Bz-ATP-induced Ca2+ flux after 30 mins by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity at human P2X7 receptor expressed in 1321N1 cells assessed as inhibition of Bz-ATP-induced Ca2+ flux after 30 mins by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high ...More data for this Ligand-Target Pair
Affinity DataIC50: 122nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human, rat or mouse P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high ...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Radioligand binding: human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparation...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according ...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Radioligand binding: human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparation...More data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according ...More data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair