BDBM159976 US10093663, Example 20b::US9682968, Example-20b

SMILES COc1cc(C)c2[nH]ccc2c1CN1CC[C@H](C)C[C@@H]1c1ccc(cc1)C(O)=O

InChI Key InChIKey=JRMYPSCIGHXTAS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 159976   

TargetComplement factor B(Human)
Novartis

US Patent
LigandPNGBDBM159976(US9682968, Example-20b | US10093663, Example 20b)
Affinity DataIC50: 0.290nMAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 uM), recombinant human complement factor B (expressed in drosophila cells and purified us...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetComplement factor B(Human)
Novartis

US Patent
LigandPNGBDBM159976(US9682968, Example-20b | US10093663, Example 20b)
Affinity DataIC50: 290nMpH: 7.4 T: 2°CAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
In DepthDetails
US Patent