BDBM159294 US10093663, Example 8::US9682968, Example-8

SMILES Cc1cc(C)c2[nH]ccc2c1CN1CCCCC1c1ccc(cc1)C(N)=O

InChI Key InChIKey=HVCYKNQNKTXZHC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 159294   

TargetComplement factor B(Human)
Novartis

US Patent
LigandPNGBDBM159294(US9682968, Example-8 | US10093663, Example 8)
Affinity DataIC50: 0.710nMAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 uM), recombinant human complement factor B (expressed in drosophila cells and purified us...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetComplement factor B(Human)
Novartis

US Patent
LigandPNGBDBM159294(US9682968, Example-8 | US10093663, Example 8)
Affinity DataIC50: 710nMpH: 7.4 T: 2°CAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetComplement factor B(Human)
Novartis

US Patent
LigandPNGBDBM159294(US9682968, Example-8 | US10093663, Example 8)
Affinity DataIC50: 710nMAssay Description:Inhibition of human serine protease factor B by TR-FRET based competition binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed