BDBM159169 US10195186, Example 30::US9682967, 29

SMILES OC(=O)c1cc(Br)ccc1C(=O)Nc1ccc2ccccc2n1

InChI Key InChIKey=RNQLAUVLLWNETM-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 159169   

TargetSortilin(Human)
H. Lundbeck

US Patent
LigandPNGBDBM159169(US9682967, 29 | US10195186, Example 30)
Affinity DataIC50: 2.10E+3nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetSortilin(Human)
H. Lundbeck

US Patent
LigandPNGBDBM159169(US9682967, 29 | US10195186, Example 30)
Affinity DataKi:  1.24E+3nM IC50: 1.30E+3nMpH: 7.4Assay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
Go to US Patent

TargetSortilin(Human)
H. Lundbeck

US Patent
LigandPNGBDBM159169(US9682967, 29 | US10195186, Example 30)
Affinity DataKi:  2.00E+3nMAssay Description:The Sortilin assay was performed in total volume of 40 ul in 50 mM HEPES pH 7.4 assay buffer containing 100 mM NaCl, 2.0 mM CaCl2, 0.1% BSA and 0.1% ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent