BDBM158403 US9029381, 42::US9029381, 43::US9029381, 44

SMILES NC(=O)c1ccc(cc1)C1CC1C(=O)N1CCN(CC1)C1CCC1

InChI Key InChIKey=VCQZCDSEWSFTPO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 158403   

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158403(US9029381, 44 | US9029381, 43 | US9029381, 42)
Affinity DataIC50: 14.4nMAssay Description:The H3 binding assay was/can be used to evaluate the ability of at least one compound in accordance with formula I, Ia, Ib, and/or Ic to inhibit [3H]...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158403(US9029381, 44 | US9029381, 43 | US9029381, 42)
Affinity DataIC50: 5.83nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158403(US9029381, 44 | US9029381, 43 | US9029381, 42)
Affinity DataIC50: 3.81nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistamine H3 receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM158403(US9029381, 44 | US9029381, 43 | US9029381, 42)
Affinity DataIC50: 834nMpH: 7.4 T: 2°CAssay Description:A GTP gamma S binding assay can be used to investigate antagonist properties of compounds in CHO cells (Chinese Hamster Ovary) transfected with human...More data for this Ligand-Target Pair
In DepthDetails
US Patent