BDBM15749 1-[2-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}phenyl)ethyl]cyclopentan-1-ol::[5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-{3-[2-(1-hydroxycyclopentyl)ethyl]phenyl}methanone::aminopyrazole 47

SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(CCC2(O)CCCC2)c1

InChI Key InChIKey=BSNOOUBZAZNTTC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15749   

TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15749([5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-{3-[2...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed