BDBM15748 1-(4-fluorophenyl)-4-{[3-(2-methanesulfonylethyl)phenyl]carbonyl}-1H-pyrazol-5-amine::[5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(2-methanesulfonylethyl)phenyl]methanone::aminopyrazole 46

SMILES CS(=O)(=O)CCc1cccc(c1)C(=O)c1cnn(c1N)-c1ccc(F)cc1

InChI Key InChIKey=FAOCNBXKNCERRY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15748   

TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15748(1-(4-fluorophenyl)-4-{[3-(2-methanesulfonylethyl)p...)
Affinity DataIC50: 790nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed