BDBM15732 4-({3-[3-(dimethylamino)prop-1-yn-1-yl]phenyl}carbonyl)-1-(4-fluorophenyl)-1H-pyrazol-5-amine::[5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(3-(dimethylamino)prop-1-ynyl)phenyl]methanone::aminopyrazole 34

SMILES CN(C)CC#Cc1cccc(c1)C(=O)c1cnn(c1N)-c1ccc(F)cc1

InChI Key InChIKey=VGELWLMQVSZFKX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15732   

TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15732([5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(3...)
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed