BDBM15677 1-cyclohexyl-N-(3,5-dichlorophenyl)-5-oxopyrrolidine-3-carboxamide::Pyrrolidine Carboxamide Compound d11

SMILES Clc1cc(Cl)cc(NC(=O)C2CN(C3CCCCC3)C(=O)C2)c1

InChI Key InChIKey=YUFADRZDHJKVOT-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15677   

TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of California San Francisco

LigandPNGBDBM15677(1-cyclohexyl-N-(3,5-dichlorophenyl)-5-oxopyrrolidi...)
Affinity DataIC50: 390nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of California San Francisco

LigandPNGBDBM15677(1-cyclohexyl-N-(3,5-dichlorophenyl)-5-oxopyrrolidi...)
Affinity DataIC50: 390nMAssay Description:Inhibition of Mycobacterium tuberculosis InhA using 2-trans-dodecenoyl-CoA as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)