BDBM156406 US9018381, 29::US9248140, 29

SMILES CCOP(=O)(OCC)O[C@H](C1CCN(CC1)c1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(N[C@H](CCN2CCOCC2)CSc2ccccc2)c(c1)S(=O)(=O)C(F)(F)F)c1ccccc1-c1ccc(Cl)cc1

InChI Key InChIKey=KJKHZPXTVKCPIW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 156406   

TargetBcl-2-like protein 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM156406(US9018381, 29 | US9248140, 29)
Affinity DataIC50: 12nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApoptosis regulator Bcl-2(Human)
Astrazeneca

US Patent
LigandPNGBDBM156406(US9018381, 29 | US9248140, 29)
Affinity DataIC50: 30nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandPNGBDBM156406(US9018381, 29 | US9248140, 29)
Affinity DataIC50: 12nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandPNGBDBM156406(US9018381, 29 | US9248140, 29)
Affinity DataIC50: 30nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In DepthDetails
US Patent