BDBM156388 US9018381, 11::US9248140, 11

SMILES CN(CCO)CC[C@H](CSc1ccccc1)Nc1ccc(cc1S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCC(CC1)[C@@H](N)c1ccccc1-c1ccc(Cl)cc1

InChI Key InChIKey=NMQFUMLYFHPROZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 156388   

TargetBcl-2-like protein 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM156388(US9018381, 11 | US9248140, 11)
Affinity DataIC50: 3nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApoptosis regulator Bcl-2(Human)
Astrazeneca

US Patent
LigandPNGBDBM156388(US9018381, 11 | US9248140, 11)
Affinity DataIC50: 4nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandPNGBDBM156388(US9018381, 11 | US9248140, 11)
Affinity DataIC50: 3nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandPNGBDBM156388(US9018381, 11 | US9248140, 11)
Affinity DataIC50: 4nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In DepthDetails
US Patent