BDBM156376 US9018381, 1::US9248140, 1

SMILES OCCN1CCN(CC[C@H](CSc2ccccc2)Nc2ccc(cc2S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)c2ccc(cc2)N2CCC(CC2)[C@@H](O)c2ccccc2-c2ccc(Cl)cc2)CC1

InChI Key InChIKey=DCHCBRYRKFZMDP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 156376   

TargetBcl-2-like protein 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM156376(US9018381, 1 | US9248140, 1)
Affinity DataIC50: 1nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
Astrazeneca

US Patent
LigandPNGBDBM156376(US9018381, 1 | US9248140, 1)
Affinity DataIC50: 1nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
Go to US Patent

TargetBcl-2-like protein 1 [1-209](Human)
Astrazeneca

US Patent
LigandPNGBDBM156376(US9018381, 1 | US9248140, 1)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2 [1-204](Human)
Astrazeneca

US Patent
LigandPNGBDBM156376(US9018381, 1 | US9248140, 1)
Affinity DataIC50: 1nMpH: 7.5Assay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-c) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
Go to US Patent