BDBM15517 (3R, 4R)-1-(6-Phenylpyrimidin-4-yl)-4-(2, 4, 5-trifluorophenyl)piperidin-3-amine::(3R,4R)-1-(6-phenylpyrimidin-4-yl)-4-(2,4,5-trifluorophenyl)piperidin-3-amine::Piperidine-Constrained Phenethylamine 41

SMILES N[C@H]1CN(CC[C@@H]1c1cc(F)c(F)cc1F)c1cc(ncn1)-c1ccccc1

InChI Key InChIKey=REJDGNMNCOTUBO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15517   

TargetDipeptidyl peptidase 4(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM15517((3R,4R)-1-(6-phenylpyrimidin-4-yl)-4-(2,4,5-triflu...)
Affinity DataKi:  6nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Prosidion

Curated by ChEMBL
LigandPNGBDBM15517((3R,4R)-1-(6-phenylpyrimidin-4-yl)-4-(2,4,5-triflu...)
Affinity DataKi:  6.10nM ΔG°:  -11.1kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed