BDBM15485 (+/-) racemate::(3R,4S)-4-(2,4-dichlorophenyl)-1-(4-phenylpyrimidin-2-yl)pyrrolidin-3-amine::Pyrrolidine-constrained phenethylamine 18d

SMILES N[C@H]1CN(C[C@@H]1c1ccc(Cl)cc1Cl)c1nccc(n1)-c1ccccc1

InChI Key InChIKey=ANEZVMLVQSLOFS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15485   

TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM15485((3R,4S)-4-(2,4-dichlorophenyl)-1-(4-phenylpyrimidi...)
Affinity DataKi:  140nM ΔG°:  -9.25kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2007
Entry Details Article
PubMed