BDBM15344 2-({2,3,5,6-tetrafluoro-4-[3-(trifluoromethoxy)phenyl]phenyl}carbamoyl)cyclopent-1-ene-1-carboxylic acid::CHEMBL154623::Compound 5

SMILES OC(=O)C1=C(CCC1)C(=O)Nc1c(F)c(F)c(c(F)c1F)-c1cccc(OC(F)(F)F)c1

InChI Key InChIKey=HXVDQTDBVMYWOO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 15344   

LigandPNGBDBM15344(2-({2,3,5,6-tetrafluoro-4-[3-(trifluoromethoxy)phe...)
Affinity DataIC50: 7nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM15344(2-({2,3,5,6-tetrafluoro-4-[3-(trifluoromethoxy)phe...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM15344(2-({2,3,5,6-tetrafluoro-4-[3-(trifluoromethoxy)phe...)
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminally truncated recombinant human dihydroorotate dehydrogenase using in vitro enzyme assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM15344(2-({2,3,5,6-tetrafluoro-4-[3-(trifluoromethoxy)phe...)
Affinity DataIC50: 422nMAssay Description:Inhibitory activity against mouse dihydroorotate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM15344(2-({2,3,5,6-tetrafluoro-4-[3-(trifluoromethoxy)phe...)
Affinity DataIC50: 78nMAssay Description:Inhibitory activity against rat dihydroorotate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM15344(2-({2,3,5,6-tetrafluoro-4-[3-(trifluoromethoxy)phe...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human DHODHMore data for this Ligand-Target Pair
In DepthDetails
PubMed