BDBM153128 US8993631, 36

SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)NC(=O)CCC(O)=O)C(O)=O

InChI Key InChIKey=OFCQCSHBABYJSE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 153128   

TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM153128(US8993631, 36)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
Go to US Patent

TargetNeprilysin(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM153128(US8993631, 36)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant human NEP expressed in insect cells preincubated for 1 hr using Cys(PT14)-Arg-Arg-Leu-Trp-OH as substrate and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed