BDBM152223 BDBM50304511::US8993552, 27

SMILES CCc3cc2c(N1CCN(C)CC1)ncnc2s3

InChI Key InChIKey=ZAYUCMVNISSUTM-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 152223   

TargetMenin(Human)
University of Michigan

US Patent
LigandPNGBDBM152223(US8993552, 27 | BDBM50304511)
Affinity DataIC50: 1.70E+5nMAssay Description:Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details
Go to US Patent

TargetMenin(Human)
University of Michigan

US Patent
LigandPNGBDBM152223(US8993552, 27 | BDBM50304511)
Affinity DataIC50: 3.50E+5nMAssay Description:Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details
Go to US Patent

TargetHistamine H4 receptor(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM152223(US8993552, 27 | BDBM50304511)
Affinity DataKi:  6.60E+3nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed