BDBM15220 4-Methylisoquinoline-5-sulfonic acid (2S,4S)-(2-(4-chlorobenzyloxymethyl)pyrrolidin-2-yl)amide::N-[(3S,5S)-5-{[(4-chlorophenyl)methoxy]methyl}pyrrolidin-3-yl]-4-methylisoquinoline-5-sulfonamide::isoquinoline-5-sulfonamide 61

SMILES Cc1cncc2cccc(c12)S(=O)(=O)N[C@@H]1CN[C@H](COCc2ccc(Cl)cc2)C1

InChI Key InChIKey=XMCBAQARNKQWJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15220   

TargetRAC-beta serine/threonine-protein kinase(Human)
Uk Centre For Cancer Therapeutics

LigandPNGBDBM15220(N-[(3S,5S)-5-{[(4-chlorophenyl)methoxy]methyl}pyrr...)
Affinity DataIC50: 2.60E+3nMAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bovine)
Uk Centre For Cancer Therapeutics

LigandPNGBDBM15220(N-[(3S,5S)-5-{[(4-chlorophenyl)methoxy]methyl}pyrr...)
Affinity DataIC50: 320nMAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed