BDBM151259 BDBM151425::US8987314, B55

SMILES CC(=O)Nc1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)CCC(F)(F)F

InChI Key InChIKey=UODAWRPWTNYGSU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 151259   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151259(US8987314, B55 | BDBM151425)
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151259(US8987314, B55 | BDBM151425)
Affinity DataIC50: 0.800nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151259(US8987314, B55 | BDBM151425)
Affinity DataIC50: 55nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151259(US8987314, B55 | BDBM151425)
Affinity DataIC50: 55.3nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails
US Patent