BDBM151120 US8987273, 7-0

SMILES NC1(CCC1)c1ccc(cc1)-c1nn2c(c(Cl)nc2cc1-c1ccccc1)-c1ccc(F)cc1

InChI Key InChIKey=PGJJYACDBUZJAI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151120   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM151120(US8987273, 7-0)
Affinity DataIC50: 99nMpH: 7.5 T: 2°CAssay Description:Akt1 inhibitory activity of compounds of the present invention was quantified employing the Akt1 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM151120(US8987273, 7-0)
Affinity DataIC50: 106nMpH: 7.5 T: 2°CAssay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
In DepthDetails
US Patent