BDBM150686 US8987254, 1::US9999624, 1

SMILES NC1=N[C@]2(CN(C[C@H]2CS1)c1ncc(F)cn1)c1cccc(NC(=O)c2ccc(F)cn2)c1

InChI Key InChIKey=ZTBLMRQYSTZEMI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 150686   

TargetBeta-secretase 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM150686(US8987254, 1 | US9999624, 1)
Affinity DataIC50: 0.610nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM150686(US8987254, 1 | US9999624, 1)
Affinity DataIC50: 0.610nMAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20× in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
In DepthDetails
US Patent