BDBM149374 US8962860, 41

SMILES Fc1ccc(C2N(C(=O)NC2=S)c2ccc3nc[nH]c3c2)c(F)c1F

InChI Key InChIKey=NGJZDGZTGWZQHU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 149374   

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM149374(US8962860, 41)
Affinity DataKi:  85.3nM ΔG°:  -9.80kcal/mole IC50: 485nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2015
Entry Details
Go to US Patent