BDBM14819 (1E)-1-[(6-chloro-2H-1,3-benzodioxol-5-yl)methylidene]-2-{5H-[1,2,4]triazino[5,6-b]indol-3-yl}hydrazine::Chembridge compound 6

SMILES Clc1cc2OCOc2cc1CN=Nc1nnc2c(n1)[nH]c1ccccc21

InChI Key InChIKey=SCTVRXQQPWBIGS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14819   

TargetSerine/threonine-protein kinase Chk1(Human)
Vernalis (R&D)

LigandPNGBDBM14819((1E)-1-[(6-chloro-2H-1,3-benzodioxol-5-yl)methylid...)
Affinity DataIC50: 2.01E+4nMpH: 7.5 T: 2°CAssay Description:Chk1 kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P] ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2007
Entry Details Article
PubMed