BDBM14817 4-{[5-(5-chloro-2-methoxyphenyl)-1,3,4-thiadiazol-2-yl]amino}benzoic acid::InterBioScreen compound 4

SMILES COc1ccc(Cl)cc1-c1nnc(Nc2ccc(cc2)C(O)=O)s1

InChI Key InChIKey=NAFOYEZWBFPHOE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14817   

TargetSerine/threonine-protein kinase Chk1(Human)
Vernalis (R&D)

LigandPNGBDBM14817(4-{[5-(5-chloro-2-methoxyphenyl)-1,3,4-thiadiazol-...)
Affinity DataIC50: 2.66E+4nMpH: 7.5 T: 2°CAssay Description:Chk1 kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P] ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2007
Entry Details Article
PubMed