BDBM14816 6-amino-4-(3,4-dihydroxyphenyl)-3-methyl-1H,4H-pyrano[2,3-c]pyrazole-5-carbonitrile::Asinex compound 3

SMILES Cc1[nH]nc2OC(=N)C(C#N)C(c12)c1ccc(O)c(O)c1

InChI Key InChIKey=FKKCHFSMHOTUGA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14816   

TargetSerine/threonine-protein kinase Chk1(Human)
Vernalis (R&D)

LigandPNGBDBM14816(6-amino-4-(3,4-dihydroxyphenyl)-3-methyl-1H,4H-pyr...)
Affinity DataIC50: 2.04E+4nMpH: 7.5 T: 2°CAssay Description:Chk1 kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P] ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2007
Entry Details Article
PubMed