BDBM145726 US8952177, 80::US9089569, 80::US9695149, 80

SMILES Cc1ccc(COc2ccc3nc(C4CCCCC4)n(Cc4ccc(cc4)-c4ncc(Cl)cn4)c3c2)nc1

InChI Key InChIKey=UNWDHUIJLMMKMA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 145726   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM145726(US8952177, 80 | US9695149, 80 | US9089569, 80)
Affinity DataKi:  3.30nMAssay Description:FLAP-containing membranes were prepared as was a FITC-labeled FLAP modulator (3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM145726(US8952177, 80 | US9695149, 80 | US9089569, 80)
Affinity DataKi:  3.30nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In DepthDetails
US Patent