BDBM143160 US8940739, G-63

SMILES COC1CCN(CC1)C1CN(C1)c1ccc(NC(=O)c2cn(C)c3c(CN4C[C@H]5N([C@@H](Cc6ccc(O)cc6)C4=O)C(=O)CN(CC=C)N5C(=O)NCc4ccccc4)cccc23)cn1

InChI Key InChIKey=NYWLSHWADDPCKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 143160   

TargetCytochrome P450 3A4(Human)
Jw Pharmaceutical

US Patent
LigandPNGBDBM143160(US8940739, G-63)
Affinity DataIC50: 2.56E+3nMpH: 7.4Assay Description:This assay was performed in a 200 l volume in 96-well microtiter plates using cDNA-expressed human hepatic CYP3A4 (supersome, BD Gentest #456202). As...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2015
Entry Details
Go to US Patent