BDBM143115 US8940739, G-18

SMILES CN(CCO)c1ccc(NC(=O)c2cn(C)c3c(CN4C[C@@H]5N(N(CC=C)CC(=O)N5[C@@H](Cc5ccc(O)cc5)C4=O)C(=O)NCc4ccccc4)cccc23)cn1

InChI Key InChIKey=NESCTSGARYERBV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 143115   

TargetCytochrome P450 3A4(Human)
Jw Pharmaceutical

US Patent
LigandPNGBDBM143115(US8940739, G-18)
Affinity DataIC50: 3.45E+3nMpH: 7.4Assay Description:This assay was performed in a 200 l volume in 96-well microtiter plates using cDNA-expressed human hepatic CYP3A4 (supersome, BD Gentest #456202). As...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2015
Entry Details
Go to US Patent