BDBM142919 BDBM420091::US11136327, Example I-124::US8940720, I-124
SMILES Clc1ccc(c(\C=C\C(=O)N[C@H]2CCCCCNc3cc(NC(=O)OC[C@H]4CCCO4)ccc3-c3c[nH]c2n3)c1)-n1cnnn1
InChI Key InChIKey=DZTIZOIMYLLLKV-UHFFFAOYSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 142919
Affinity DataKi: <5nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
Affinity DataKi: <5nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
Affinity DataKi: <5nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair