BDBM142836 US8940736, 408

SMILES CCNc1nc(Nc2cc(cc(N3CCN(CC3)C3COC3)c2Cl)C#N)nn2c(cnc12)C#N

InChI Key InChIKey=HJGJLSSJJLDPPL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 142836   

TargetCasein kinase II subunit alpha(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM142836(US8940736, 408)
Affinity DataIC50: 1.39nMpH: 7.4 T: 2°CAssay Description:The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
Go to US Patent

TargetCasein kinase II subunit alpha'(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM142836(US8940736, 408)
Affinity DataIC50: 0.230nMpH: 7.4 T: 2°CAssay Description:The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
Go to US Patent