BDBM142825 US8940736, 364

SMILES CCNc1nc(Nc2cc(cc(N3CCC(CC3)NC[C@@H](C)O)c2Cl)C#N)nn2c(cnc12)[N+]#[C-]

InChI Key InChIKey=AWWDSLVZIXRDDE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 142825   

TargetCasein kinase II subunit alpha(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM142825(US8940736, 364)
Affinity DataIC50: 1.33nMpH: 7.4 T: 2°CAssay Description:The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
Go to US Patent

TargetCasein kinase II subunit alpha'(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM142825(US8940736, 364)
Affinity DataIC50: 0.610nMpH: 7.4 T: 2°CAssay Description:The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
Go to US Patent