BDBM142605 US8933228, 7
SMILES Cc1nc2c(Oc3ccc(NC(=O)Nc4cc(nn4-c4ccccc4)C(C)(C)C)c4ccccc34)ccnc2[nH]c1=O
InChI Key InChIKey=GWOFQUMBWYKHFL-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 142605
Affinity DataIC50: 3nMAssay Description:The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of B-Raf V600E mutantMore data for this Ligand-Target Pair