BDBM142183 US8933079, 5.2

SMILES CN(C)Cc1ccc(C(=O)Cn2ncc(OCc3ccccc3)cc2=O)c(C)c1

InChI Key InChIKey=DHFJGWKDFMSSAN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 142183   

TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM142183(US8933079, 5.2)
Affinity DataIC50: 9nMpH: 7.0Assay Description:Membranes from CHO/Galpha16 cells stably transfected with human hMCH-1R are resuspended using a syringe (needle 0.6x25 mm) and diluted in test buffer...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMelanin-concentrating hormone receptor 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM142183(US8933079, 5.2)
Affinity DataIC50: 8.70nMAssay Description:Displacement of [125I]-MCH from human MCH-R1 expressed in CHO/Galpha16 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed