BDBM139606 US8889870, 152::US9388176, 152::US9820989, 152

SMILES Cc1ccc(cc1N1CCc2ncncc2C1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=GMTKASDZTJJXAZ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 139606   

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM139606(US8889870, 152 | US9388176, 152 | US9820989, 152)
Affinity DataIC50: 104nMpH: 7.4Assay Description:Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 .mu.g/well of poly-Glu-Tyr (4:1) in 10 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM139606(US8889870, 152 | US9388176, 152 | US9820989, 152)
Affinity DataIC50: 104nMpH: 7.4 T: 2°CAssay Description:Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM139606(US8889870, 152 | US9388176, 152 | US9820989, 152)
Affinity DataKi:  104nMAssay Description:Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...More data for this Ligand-Target Pair
In DepthDetails
US Patent