BDBM139472 US8889672, 252-036-001

SMILES COc1ccc(cc1OC)-c1csc(N)c1C(=O)OCc1ccccc1

InChI Key InChIKey=DXFCCKZJJXVRFH-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 139472   

TargetProtein kinase C zeta type(Human)
University of Michigan

US Patent
LigandPNGBDBM139472(US8889672, 252-036-001)
Affinity DataIC50: 6.00E+3nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein kinase C zeta type(Human)
University of Michigan

US Patent
LigandPNGBDBM139472(US8889672, 252-036-001)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of atypical PKCzeta (unknown origin) using CREBtide as substrate incubated for 1 hr measured every 2.5 mins by ADP Quest assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C zeta type(Human)
University of Michigan

US Patent
LigandPNGBDBM139472(US8889672, 252-036-001)
Affinity DataEC50:  2nMAssay Description:Inhibition of atypical PKCzeta in HEK293 cells assessed as TNF-induced NFkappaB activation incubated for 3 hrs prior to TNF induction measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed