BDBM138311 US8877944, 15

SMILES NC(=O)c1cccc2CN(C3CCN(Cc4ccc(cc4)C(F)(F)F)CC3)C(=O)c12

InChI Key InChIKey=FRWIIFSPNRVERL-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 138311   

TargetPoly [ADP-ribose] polymerase 1(Mouse)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM138311(US8877944, 15)
Affinity DataKd:  50nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM138311(US8877944, 15)
Affinity DataKd:  54nMAssay Description:Binding affinity to full length recombinant human PARP-1 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM138311(US8877944, 15)
Affinity DataKd:  3.63E+3nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed