BDBM136544 US8865701, 3::US9505739, 3

SMILES COc1cccc2c1OCC[C@]21CNC[C@H]1C(=O)N1CC[C@H](C[C@H]1C1CCCC(F)(F)C1)c1ccccc1

InChI Key InChIKey=QDJWLSPATDJTJC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 136544   

TargetBeta-secretase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM136544(US8865701, 3 | US9505739, 3)
Affinity DataIC50: 2.19E+3nMpH: 6.5Assay Description:A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM136544(US8865701, 3 | US9505739, 3)
Affinity DataIC50: 2.19E+3nMpH: 6.5Assay Description:A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate...More data for this Ligand-Target Pair
In DepthDetails
US Patent