BDBM13569 2-[(4-carbamimidoylphenyl)amino]-2-{3-ethynyl-5-[(3R)-oxolan-3-yloxy]phenyl}acetic acid::phenylglycine deriv. 17

SMILES NC(=N)c1ccc(NC(C(O)=O)c2cc(O[C@@H]3CCOC3)cc(c2)C#C)cc1

InChI Key InChIKey=VMITUNZSHSJLHI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13569   

TargetCoagulation factor VII(Human)
F. Hoffmann-La Roche

LigandPNGBDBM13569(2-[(4-carbamimidoylphenyl)amino]-2-{3-ethynyl-5-[(...)
Affinity DataKi:  129nM ΔG°:  -9.30kcal/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

LigandPNGBDBM13569(2-[(4-carbamimidoylphenyl)amino]-2-{3-ethynyl-5-[(...)
Affinity DataKi:  6.60E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

LigandPNGBDBM13569(2-[(4-carbamimidoylphenyl)amino]-2-{3-ethynyl-5-[(...)
Affinity DataKi:  8.80E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
F. Hoffmann-La Roche

LigandPNGBDBM13569(2-[(4-carbamimidoylphenyl)amino]-2-{3-ethynyl-5-[(...)
Affinity DataKi:  1.53E+4nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed