BDBM13546 3-(3,4,5-Trimethoxyphenyl)-N-(2-oxo-2-(2-(1,2,3,4-tetrahydroacridin-9-yl)hydrazino)-ethyl)propanamide::N-[(N'-1,2,3,4-tetrahydroacridin-9-ylhydrazinecarbonyl)methyl]-3-(3,4,5-trimethoxyphenyl)propanamide::tacrine derivative 16b

SMILES COc1cc(CCC(=O)NCC(=O)NNc2c3CCCCc3nc3ccccc23)cc(OC)c1OC

InChI Key InChIKey=LHUNFEXUROHDNV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13546   

TargetAcetylcholinesterase(Human)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM13546(N-[(N'-1,2,3,4-tetrahydroacridin-9-ylhydrazinecarb...)
Affinity DataIC50: 40.7nMpH: 7.3 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changed at 412 nm and was monitored with spectr...More data for this Ligand-Target Pair
In DepthDetails Article
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TargetCholinesterase(Human)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM13546(N-[(N'-1,2,3,4-tetrahydroacridin-9-ylhydrazinecarb...)
Affinity DataIC50: 24nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changed at 412 nm and was monitored with spectr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Pacific electric ray)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM13546(N-[(N'-1,2,3,4-tetrahydroacridin-9-ylhydrazinecarb...)
Affinity DataIC50: 40.1nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changed at 412 nm and was monitored with spectr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Rheinische Friedrich-Wilhelms-Universitat Bonn

LigandPNGBDBM13546(N-[(N'-1,2,3,4-tetrahydroacridin-9-ylhydrazinecarb...)
Affinity DataIC50: 122nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changed at 412 nm and was monitored with spectr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed